树枝状大分子
佐剂
纳米颗粒
输送系统
表位
材料科学
纳米技术
医学
生物医学工程
高分子化学
免疫学
抗体
作者
Mariusz Skwarczyński,Mehfuz Zaman,Carl N. Urbani,I‐Chun Lin,Zhongfan Jia,Michael R. Batzloff,Michael F. Good,Michael J. Monteiro,István Tóth
标识
DOI:10.1002/anie.201002221
摘要
Special delivery: An effective group A streptococci vaccine is formed from a delivery device consisting of well-defined dendritic structures with nanoscale dimensions (see picture). The structures are designed to display multiple copies of the minimal B-cell epitopes, which were in the optimal conformation on the surface of the nanoparticles. The nanoparticles can be administered without the aid of an adjuvant.
科研通智能强力驱动
Strongly Powered by AbleSci AI