In this paper, we propose a quantum interference mediated control of switching between magnon-atom entanglement and magnon blockade. A three-level $\mathrm{\ensuremath{\Lambda}}$ configuration atomic ensemble and a yttrium iron garnet sphere are simultaneously coupled to a microwave cavity mode through magnetic dipole interaction. By applying two strong fields to drive the atoms, the resonant coupling between a dressed-state atomic transition and the magnon mode, without direct interaction, is established by adiabatically eliminating the cavity field. Interestingly, the anti-Jaynes-Cummings (JC) interaction and the JC interaction are alternatively formed when the atoms are trapped into different superposition states induced by quantum interference, causing the appearance of hybrid magnon-atom entanglement and magnon quantum blockade, respectively. The coherent-controlled hybrid magnon-atom entanglement and magnon blockade may find potential applications in quantum information processing.