Synthesis and Biological Activity of 2‐Adamantanone Oxime Carbamate Derivatives

Abstract The synthesis of a number of new 2‐adamantanone oxime carbamate derivatives (7a‐h) is described. When tested in the carrageenin‐induced rat paw edema assay, some of the compounds exerted moderate anti‐inflammatory activity. In addition, the title 2‐adamantanone oxime carbamates showed in vitro antifungal activity against yeast and systemic mycoses and dermatophytes.