化学
立体化学
自然(考古学)
绝对构型
组合化学
生物
古生物学
出处
期刊:Journal of International Pharmaceutical Research
日期:2015-01-01
被引量:5
摘要
The difficulty in the structure elucidation of natural products is in the elucidation of stereochemistry,especially the determination of absolute configuration,which generally involves the key techniques of structure elucidation of natural products.This paper shows some examples of our work in elucidating the stereochemistry of new chiral natural products by the application of several physicochemical techniques,such as the dimolybdenum tetraacetate[Mo2(OAc)4]induced CD(ICD,Snatzke′s method),empirical rules of classical CD,modified Mosher′s method,theoretical ECD calculation and modified Marfey′s analysis. The fundamental rules of the techniques and our experiences in the application of these techniques are also described for related researcher′s reference in relevant studies.
科研通智能强力驱动
Strongly Powered by AbleSci AI