尤登J统计
金标准(测试)
抗体
弓形虫
病毒学
免疫学
生物
医学
接收机工作特性
内科学
作者
Ya-Xiao Yang,Yukun Chen,Shijin Wei,Ren-Hao Song
出处
期刊:PubMed
日期:2014-02-01
卷期号:26 (1): 109-10
被引量:7
摘要
To discuss the test efficiency of three methods for detecting Toxoplasma IgG antibody.Totally 304 specimens were detected parallelly for Toxoplasma IgG antibody by using the gold marked method, indirect hemagglutination test (IHA), and enzyme-linked immunosorbent assay (ELISA), and the sensitivity, specificity and Youden index of these methods were compared.The detection sensitivities of gold marked method, IHA, and ELISA for Toxoplasma IgG antibody were 85.5%, 89.8% and 91.9% respectively (chi2 = 4.12, P > 0.05); the specificities were 92.4%, 96.6% and 97.5% respectively (chi2 = 4.06, P > 0.05). The detection efficiency and Youden index of ELISA were 94.1% and 0.89 respectively, being higher than those of IHA and gold marked method.The sensitivity and specificity of the ELISA method for Toxoplasma IgG antibody are higher, and in addition, it can be automated. Therefore, it is suitable for large-scale Toxoplasma IgG antibody screening.
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