Recent Progress in Beckmann Rearrangement

Amide motifs are prevalent structures found in natural products, pharmaceuticals, and bioactive compounds.Amide bond formations are the most important transformations in organic chemistry.Beckmann rearrangement is a significant method for the synthesis of primary and secondary amides.Recently, diversified new catalytic protocols were developed, including one-pot reaction from the corresponding aldehydes and ketones, or even from alcohols.The progress and applications of Beckmann rearrangement in recent five years are reviewed.