医学
肺癌
杜瓦卢马布
癌症
依托泊苷
肿瘤科
免疫疗法
内科学
斯科普斯
入射(几何)
无容量
化疗
梅德林
法学
物理
光学
政治学
作者
Thorsten Oliver Goetze
出处
期刊:The Lancet
[Elsevier BV]
日期:2019-10-04
卷期号:394 (10212): 1884-1885
被引量:14
标识
DOI:10.1016/s0140-6736(19)32235-4
摘要
Lung cancer is the most frequently diagnosed cancer (11·6% of all cancer cases) and the leading cause of deaths due to cancer (18·4% of all cancer deaths). 1 Bray F Ferlay J Soerjomataram I et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018; 68: 394-424 Crossref PubMed Scopus (41701) Google Scholar About 15% of all diagnosed lung cancers are small-cell lung cancer (SCLC) and up to 60–70% of these are extensive-stage SCLC (ES-SCLC) at initial diagnosis. 2 Oronsky B Reid TR Oronsky A Carter CA What's new in SCLC? A review. Neoplasia. 2017; 19: 842-847 Crossref PubMed Scopus (76) Google Scholar , 3 Wang S Tang J Sun T et al. Survival changes in patients with small cell lung cancer and disparities between different sexes, socioeconomic statuses and ages. Sci Rep. 2017; 71339 Crossref PubMed Scopus (72) Google Scholar Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trialFirst-line durvalumab plus platinum–etoposide significantly improved overall survival in patients with ES-SCLC versus a clinically relevant control group. Safety findings were consistent with the known safety profiles of all drugs received. Full-Text PDF
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