环丙烷
光异构化
化学
催化作用
立体化学
异构化
有机化学
戒指(化学)
作者
Neng Wang,Jin‐Bu Xu,Xiaohuan Li,Xian‐Li Zhou,Feng Gao
出处
期刊:Organic Letters
[American Chemical Society]
日期:2022-11-20
卷期号:24 (47): 8598-8602
被引量:10
标识
DOI:10.1021/acs.orglett.2c03172
摘要
An efficient Ir-catalyzed biomimetic method for photoisomerization of cyclopropane in lathyrane-type Euphorbia diterpenes is reported. Lathyrane diterpenes featuring the trans-fused cyclopropane (1a–5a) were successfully prepared from cis-cyclopropane lathyranes (1–5) in excellent yields by this stereochemical permutations strategy, which first verified the biogenesis relationship between the lathyrane isomers. Moreover, 5a could further convert into another trans-isomer 5b. The present work provides a convenient route for easy access of naturally rare 12(Z)-trans-cyclopropane lathyranes.
科研通智能强力驱动
Strongly Powered by AbleSci AI