亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Outcomes in Pregnancies Complicated with Preterm Hypertensive Disorders with and without Late Antenatal Corticosteroids

医学 支气管肺发育不良 新生儿重症监护室 胎龄 呼吸窘迫 优势比 出生体重 回顾性队列研究 儿科 坏死性小肠结肠炎 阿普加评分 脑室出血 小于胎龄 怀孕 产科 外科 内科学 遗传学 生物
作者
Noam Regev,Michal Axelrod,Chen Berkovitz,Rakefet Yoeli-Ulman,Shali Mazaki‐Tovi,Eyal Sivan,Baha M. Sibai,Michal Fishel Bartal
出处
期刊:American Journal of Perinatology [Georg Thieme Verlag KG]
标识
DOI:10.1055/s-0044-1788609
摘要

Objective This study aimed to determine whether administration of a late preterm (34–36 weeks) course of antenatal corticosteroids (ACS) is associated with improved short-term neonatal outcomes among pregnancies complicated with hypertensive disorders of pregnancy (HDP) who delivered in the late preterm period. Study Design A single tertiary center retrospective cohort study, including pregnant individuals with singleton fetuses who delivered between 34.0 and 36.6 weeks following an HDP diagnosis. Exclusion criteria were major fetal anomalies and treatment with ACS before 34 weeks. Cases were divided into two groups: exposed group, consisting of individuals treated with a late ACS course, and nonexposed group, receiving no ACS. The primary outcome was a composite adverse neonatal outcome, including intensive care unit admission, oxygen treatment, noninvasive positive pressure ventilation, mechanical ventilation, respiratory distress syndrome, transient tachypnea, or apnea of prematurity. Secondary neonatal outcomes included birth weight, Apgar score, intraventricular hemorrhage, necrotizing enterocolitis, bronchopulmonary dysplasia, surfactant use, hypoglycemia, hyperbilirubinemia, sepsis, and neonatal death. Multivariable regression models were used to determine adjusted odds ratio (aOR)and 95% confidence intervals (CIs). Results Of 7,624 preterm singleton deliveries during the study period, 438 (5.7%) were diagnosed with HDP and delivered between 34.0 and 36.6 weeks. Infants who received ACS were diagnosed more commonly with fetal growth restriction (16.0 vs. 5.6%, p < 0.01) and were delivered at an earlier gestational age (GA) (mean GA: 35.6 vs. 36.3 weeks, p < 0.01). The composite neonatal morbidity did not differ between the groups after adjustments (aOR: 0.97, 95% CI: 0.47, 1.98). Neonatal hypoglycemia and hyperbilirubinemia were more common in the exposed group than in the nonexposed group (46.9 vs. 27.4%; aOR: 2.27; 95% CI: 1.26, 4.08 and 64.2 vs. 46.5%; aOR: 2.08; 95% CI: 1.16, 3.72 respectively). Conclusion In people with HDP, a course of ACS given in the late preterm period did not improve neonatal morbidity. Key Points

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
JamesPei应助andrele采纳,获得10
16秒前
17秒前
22秒前
24秒前
充电宝应助小鲤鱼在睡觉采纳,获得10
28秒前
小鲤鱼在睡觉完成签到,获得积分10
36秒前
1分钟前
andrele发布了新的文献求助30
1分钟前
CHL完成签到 ,获得积分10
1分钟前
情怀应助科研通管家采纳,获得10
1分钟前
科研通AI2S应助科研通管家采纳,获得10
1分钟前
2分钟前
andrele发布了新的文献求助10
2分钟前
3分钟前
脑洞疼应助科研通管家采纳,获得20
3分钟前
华仔应助于是乎采纳,获得10
4分钟前
iehaoang完成签到 ,获得积分10
5分钟前
h0jian09完成签到,获得积分10
5分钟前
李爱国应助科研通管家采纳,获得10
5分钟前
搜集达人应助科研通管家采纳,获得10
5分钟前
JamesPei应助科研通管家采纳,获得10
5分钟前
andrele发布了新的文献求助10
6分钟前
CCC完成签到,获得积分10
6分钟前
可乐完成签到,获得积分10
6分钟前
从容芮应助CCC采纳,获得10
6分钟前
可乐发布了新的文献求助10
6分钟前
华仔应助可乐采纳,获得10
7分钟前
kuoping完成签到,获得积分10
7分钟前
斯文败类应助科研通管家采纳,获得10
7分钟前
情怀应助科研通管家采纳,获得10
7分钟前
Raunio完成签到,获得积分10
8分钟前
8分钟前
8分钟前
汉堡包应助秋刀鱼不过期采纳,获得10
8分钟前
9分钟前
9分钟前
9分钟前
柯迎南发布了新的文献求助10
10分钟前
无花果应助柯迎南采纳,获得10
10分钟前
柯迎南完成签到,获得积分20
11分钟前
高分求助中
Sustainability in Tides Chemistry 2800
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
Rechtsphilosophie 1000
Bayesian Models of Cognition:Reverse Engineering the Mind 888
Le dégorgement réflexe des Acridiens 800
Defense against predation 800
Very-high-order BVD Schemes Using β-variable THINC Method 568
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3137011
求助须知:如何正确求助?哪些是违规求助? 2787960
关于积分的说明 7784196
捐赠科研通 2444060
什么是DOI,文献DOI怎么找? 1299705
科研通“疑难数据库(出版商)”最低求助积分说明 625497
版权声明 600997