Diagnostic Pathway Outcomes for Bi-parametric MRI Targeted Lesions Using Cognitive Registration and Freehand Transperineal Prostate Biopsy in Biopsy Naïve Men (CRAFT Single Centre Study)

Enhanced histological detection of clinically significant prostate cancer is the goal of the pre-biopsy imaging pathway. Risk stratification at a pre-biopsy meeting can facilitate optimisation of lesion targeting. We aimed to evaluate the feasibility of cognitive registration, freehand transperineal prostate biopsy in a biopsy naïve population following bi-parametric magnetic resonance imaging for the detection of clinically significant disease (International Society of Urological Pathology Grade Group ≥2).