自愈水凝胶
果胶
药物输送
纳米技术
药品
适应性
生物高聚物
控制释放
透皮
材料科学
化学
药理学
医学
聚合物
生物
有机化学
食品科学
高分子化学
生态学
作者
Devesh Kapoor,Rahul Garg,Mansi Gaur,Ashutosh Pareek,Bhupendra G. Prajapati,Guillermo R. Castro,Supakij Suttiruengwong,Pornsak Sriamornsak
标识
DOI:10.1016/j.jsps.2024.102002
摘要
Pectin hydrogels have emerged as a highly promising medium for the controlled release of pharmaceuticals in the dynamic field of drug delivery. The present review sheds light on the broad range of applications and potential of pectin-based hydrogels in pharmaceutical formulations. Pectin, as a biopolymer, is a versatile candidate for various drug delivery systems because of its wide range of properties and characteristics. The information provided on formulation strategies and crosslinking techniques provides researchers with tools to improve drug entrapment and controlled release. Furthermore, this review provides a more in-depth understanding of the complex factors influencing drug release from pectin hydrogels, such as the impact of environmental conditions and drug-specific characteristics. Pectin hydrogels demonstrate adaptability across diverse domains, ranging from applications in oral and transdermal drug delivery to contributions in wound healing, tissue engineering, and ongoing clinical trials. While standardization and regulatory compliance remain significant challenges, the future of pectin hydrogels appears to be bright, opening up new possibilities for advanced drug delivery systems.
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