表观遗传学
组蛋白
表观遗传学
生物
染色质
遗传学
DNA甲基化
组蛋白密码
后生
计算生物学
组蛋白甲基化
乙酰化
基因表达调控
基因
基因表达
核小体
出处
期刊:Epigenomics
[Future Medicine]
日期:2022-12-01
卷期号:14 (23): 1465-1477
被引量:10
标识
DOI:10.2217/epi-2022-0437
摘要
Histone proteins are a primary component of chromatin; therefore, any modifications to their structure are anticipated to affect the behavior of our genetic material, which is manifested in the form of phenotypic changes at a molecular, cellular or organic level. The majority of histone modifications are of either methylation or acetylation type that regulate gene expression. Though, not all of these modifications are concerned with the direct regulation of gene transcription. Throughout its 13-year run, Epigenomics has never ceased to cover these most gripping epigenetic stories, a significant proportion of which is in the matter of histones and their modifications. As such, the current perspective piece is intended to highlight original histone-oriented contributions published in Epigenomics since 2020.
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