医学
光动力疗法
胆道支架
外科
普通外科
支架
有机化学
化学
出处
期刊:PubMed
日期:2023-02-23
卷期号:61 (4): 265-276
标识
DOI:10.3760/cma.j.cn112139-20230115-00023
摘要
Photodynamic therapy(PDT) is an effective,minimally invasive method for tumor treatment. It can be applied for treating cholangiocarcinoma in combination with the implementation of biliary stent/external biliary drainage,or with systemic treatments including chemotherapy. Moreover,it is a primary application in the treatment of unresectable cholangiocarcinoma as well as an adjuvant treatment of residual postoperatively or locally recurrent tumors. It can control local tumor progression effectively,relieve biliary obstruction,improve life quality,and prolong survival,with the advantages of minimally invasive,precise and repeatable. To date,clinical evidence-based medicine for applying PDT to treat cholangiocarcinoma was limited,and there has been a lack of clinical specifications and consensus regarding the technique. Based on this,Group of Operative Surgery,Branch of Surgery,Chinese Medical Association,Group of Biliary Surgery,Branch of Surgery,Chinese Medical Association and Chinese Committee of Biliary Surgeons organized experts to discuss the indications,contraindications,technical protocol,efficacy evaluation,and management of complications when using PDT to treat cholangiocarcinoma. The consensus aims to provide a reference for promoting the clinical application of PDT in the treatment of cholangiocarcinoma.光动力治疗(PDT)是一种有效的肿瘤微创治疗手段,可联合胆道支架、胆道外引流、化疗等全身治疗方法治疗胆管癌,主要适用于不可手术切除胆管癌的治疗和术后肿瘤残留或局部复发的辅助性治疗,可有效控制肿瘤局部进展、解除胆道梗阻、改善患者生活质量、延长生存期,具有微创、精准及可重复等优点。目前用于胆管癌PDT的临床循证医学证据有限,缺乏临床诊疗技术规范和共识。中华医学会外科学分会外科手术学组、中华医学会外科学分会胆道外科学组及中国医师协会外科医师分会胆道外科医师委员会组织相关专家,对其适应证、禁忌证、技术操作规范、疗效评价及并发症处理等进行讨论,并达成共识,旨在为PDT在胆管癌治疗中的临床应用提供参考。.
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