医学
烧伤
吞噬作用
变形杆菌
噬菌体
微生物学
免疫
免疫学
伤口愈合
生物
大肠杆菌
免疫系统
生物化学
基因
作者
Е. Б. Лазарева,Smirnov Sv,В. Б. Хватов,Т. Г. Спиридонова,Е. Е. Биткова,О С Дарбеева,L M Maĭskaia,R L Parfeniuk,D D Men'shikov
出处
期刊:PubMed
日期:2001-01-01
卷期号:46 (1): 10-4
被引量:22
摘要
Results of clinical and laboratory evaluation of the treatment with pyobacteriophage in tablets of the patients with burn wounds are presented. It was shown that phagotherapy provided more rapid cure of pyoseptic complications, temperature normalization, wounds purification and lower lethality Bacteriological analysis of wound secretions revealed that after the treatment staphylococci and streptococci were cultured 2 times rarely, Proteus spp. Were isolated 1.5 times rarely, E. coli was not isolated. The amount of positive haemocultures also diminished. Investigation of immunologic status demonstrated statistically significant normalization of immunity on cell level. Phagocytosis level didn't change while in control group (without bacteriophage use) it became lower. Antibody level enhanced but less extensively than in control group. The results of trial demonstrates positive effect of phagotherapy use at the patients with burns.
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