The Clinical Relevance and Management of High-Flow Arteriovenous Access

医学 心脏病学 心力衰竭 心输出量 内科学 血液透析 重症监护医学 收缩性 透析 血流动力学
作者
Bhavnish Bucktowarsing,Yael Vin,Edgar V. Lerma
出处
期刊:Advances in Chronic Kidney Disease [Elsevier BV]
卷期号:27 (3): 214-218
标识
DOI:10.1053/j.ackd.2020.03.001
摘要

Obtaining an arteriovenous (AV) access for initiation of hemodialysis is considered the gold standard as it reduces risks of infections, hospitalizations, and need for interventions. It is well documented that creation of AV access can cause or aggravate heart failure. Once AV access is created, blood volume, cardiac contractility, and left ventricular end-diastolic volume increase in a nonphysiologic fashion resulting in an overall increase in cardiac output. Left ventricular hypertrophy, diastolic dysfunction, pulmonary hypertension, and high-output cardiac failure can occur. AV accesses that have blood flows greater than 1.5 L per minute are of high risk. When access flow exceeds 25% to 30% of cardiac output, the risk of developing high-output heart failure increases. Studies suggest that a blood flow (Qa)/cardiac output (CO) ratio of greater than 0.30 should be used as a screening tool to perform further cardiac testing. Depending on the severity of symptoms, management can range from banding procedure (flow reduction) or need for total abandonment of the AV access. The complications associated with high-flow AV accesses are often overlooked. Nephrologists and vascular access experts should work in tandem to mitigate potential harm to patients on dialysis who are afflicted by this condition. Obtaining an arteriovenous (AV) access for initiation of hemodialysis is considered the gold standard as it reduces risks of infections, hospitalizations, and need for interventions. It is well documented that creation of AV access can cause or aggravate heart failure. Once AV access is created, blood volume, cardiac contractility, and left ventricular end-diastolic volume increase in a nonphysiologic fashion resulting in an overall increase in cardiac output. Left ventricular hypertrophy, diastolic dysfunction, pulmonary hypertension, and high-output cardiac failure can occur. AV accesses that have blood flows greater than 1.5 L per minute are of high risk. When access flow exceeds 25% to 30% of cardiac output, the risk of developing high-output heart failure increases. Studies suggest that a blood flow (Qa)/cardiac output (CO) ratio of greater than 0.30 should be used as a screening tool to perform further cardiac testing. Depending on the severity of symptoms, management can range from banding procedure (flow reduction) or need for total abandonment of the AV access. The complications associated with high-flow AV accesses are often overlooked. Nephrologists and vascular access experts should work in tandem to mitigate potential harm to patients on dialysis who are afflicted by this condition.
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