Pharmaceutical nanotechnology has paved the road for disease diagnostics and therapeutics. Its implications in the field of health care are receiving considerable acknowledgement as it provides quicker and much cheaper treatments. With nanotechnology, it is possible to achieve efficient targeting and movement of drugs across barriers. Various pharmaceutical nanotechnology-based systems, which can be termed as nanopharmaceuticals like polymeric nanoparticles, magnetic nanoparticles, liposomes, carbon nanotubes, quantum dots, dendrimers, metallic nanoparticles, polymeric nanoparticles, etc., have brought about revolutionary changes in drug delivery as well as the total medical service system. Some useful information regarding the molecular basis of diseases has been discovered using nanotechnology. Some concerning issues like safety, bioethical issues, toxicity hazards, and physiological and pharmaceutical challenges get to be resolved by the scientists. In conclusion it is worth noting that regulators should come up with cogent guidelines to reduce/balance the risks with therapeutic outcomes. This chapter defines fabrication aspects of nano drug delivery along with its type and general idea regarding its characterization. All the systems have been supported by some recent patents for the same and appear at the end of the chapter.