Osteoporosis is a common disease of older adults and is a major public health problem worldwide. As the population ages, the incidence of osteoporosis and resulting osteoporotic fractures is increasing. Although osteoporosis is more common in women than in men, the incidence in men is increasing. The disability, mortality, and cost of hip and vertebral fractures are substantial in the rapidly growing, aging population so that prevention and treatment of osteoporosis is a major public health concern. This article reviews the impact of osteoporosis and provides an evidence-based approach toward preventing and treating osteoporosis and its complications.