美罗华
医学
硫唑嘌呤
环磷酰胺
抗中性粒细胞胞浆抗体
甲氨蝶呤
维持疗法
血管炎
ANCA相关性血管炎
显微镜下多血管炎
免疫学
内科学
抗体
强的松
化疗
疾病
作者
Loı̈c Guillevin,Christian Pagnoux,Alexandre Karras,C. Khouatra,O. Aumaître,Pascal Cohen,F. Maurier,Olivier Decaux,J. Ninet,P. Gobert,T. Quéméneur,Claire Blanchard‐Delaunay,Pascal Godmer,Xavier Puéchal,Pierre‐Louis Carron,Pierre‐Yves Hatron,Nicolas Limal,M. Hamidou,M. Ducret,Éric Daugas
标识
DOI：10.1056/nejmoa1404231
摘要
The combination of cyclophosphamide and glucocorticoids leads to remission in most patients with antineutrophil cytoplasm antibody (ANCA)–associated vasculitides. However, even when patients receive maintenance treatment with azathioprine or methotrexate, the relapse rate remains high. Rituximab may help to maintain remission.
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