Protein architecture of the yeast genome

Use of chromatin immunoprecipitation with exonuclease treatment (ChIP–exo) determines the positional organization of hundreds of chromosomal proteins throughout the Saccharomyces cerevisiae genome. The resulting ultra-high-resolution map provides insight into the regulation of genes, enhancers, replication origins, centromeres, subtelomeres and transposons. Ultra-high-resolution map of protein–chromatin interactions of the Saccharomyces cerevisiae genome.