真皮
纤维
免疫染色
胶原纤维
前胶原肽酶
胶原蛋白,I型,α1
Ⅰ型胶原
细胞外基质
解剖
化学
病理
生物
免疫组织化学
分子生物学
医学
生物化学
作者
Frank Wang,Ken Calderone,Thy Do,N. Smith,Yolanda Helfrich,Timothy R.B. Johnson,Sewon Kang,John J. Voorhees,Gary J. Fisher
摘要
Early SG display marked separation of collagen bundles and emergence of disorganized collagen fibrils that fail to form bundles. These alterations may reflect ineffective repair of collagen bundles disrupted by intense skin stretching. Persistent disruption of the collagenous extracellular matrix likely promotes formation and atrophy of SG.
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