重症肌无力
医学
神经肌肉传递
神经肌肉接头
麻醉
肌肉无力
气道
弱点
关节置换术
神经肌肉阻断剂
神经肌肉阻滞
乙酰胆碱
乙酰胆碱受体
外科
内科学
受体
心理学
神经科学
作者
JulieC. R. Misquith,ShailaS Kamath
出处
期刊:Anesthesia: Essays and Researches
日期:2018-01-01
卷期号:12 (2): 598-598
被引量:1
标识
DOI:10.4103/aer.aer_26_18
摘要
Myasthenia gravis (MG) is a neuromuscular disorder characterized by weakness and fatigability of skeletal muscles. The decrease in the number of acetylcholine receptors results in decreased efficiency of neuromuscular transmission. Although acetylcholine is released normally, it produces small end-plate potentials that fail to trigger muscle action potentials. Failure of transmission at many neuromuscular junctions results in weakness of muscle contraction. This also makes them susceptible to neuromuscular blocking agents which pose a challenge to the anesthesiologist. Here, we report a case of a patient who was a known case of MG posted for reverse shoulder arthroplasty, who was managed using a supraglottic airway device and spontaneous respiration.
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