Enantioselective synthesis of γ-tetrasubstituted nitrosulfonyl carboxylates and amides vial-tert-leucine-derived-squaramide catalyzed conjugate addition of nitrosulfones to acrylates and acrylamides

At-leucine-derived squaramide catalyzed reaction of α-nitrosulfones with acrylates/acrylamides provides γ-tetrasubstituted γ-nitro-γ-sulfonyl carboxylates/amides in excellent yield and enantioselectivity.