[Analgesic properties of pineal hormone melatonin].

Melatonin, the main hormone of the pineal gland, possesses analgesic properties, which were observed on various experimental models of pain and in the clinical practice. Such hormonal activity may be based on complex systemic and cellular mechanisms. Taking into account low toxicity of melatonin and its ability to enhance the effect of traditional analgesic agents, it is expedient to undertake broad investigation and testing of the potential of this hormonal preparation under clinical conditions.