Solid‐phase extraction of matrine and oxymatrine from Sophora Flavescens Ait using amino‐imidazolium polymer

Abstract A new, polymer‐confined, ionic liquid sorbent was developed by a process involving polymerization and modification. The obtained particles were successfully used as a special sorbent in SPE process to isolate matrine and oxymatrine from Sophora Flavescens Ait . Different washing and elution solvents, such as ethanol, methanol, acetonitrile and methanol/triethylamine (90:10, v/v), were evaluated. Compared with the C 18 and NH 2 sorbents, the amino‐imidazolium polymer sorbent exhibited higher selectivity. Quantitative analysis was carried out by using a C 18 column. The two compounds exhibited good linearity from 5×10 −3 to 0.50 mg/mL ( r 2 >0.99). The bound amounts between target compounds and proteins were obtained by this sorbent. After three recycles of amino‐imidazolium polymer, the extract amounts of the target compounds were not significantly decreased.