生物
病毒复制
复制（统计）
病毒学
DNA复制
DNA复制因子CDT1
基因
细胞周期
许可因素
病毒
遗传增强
计算生物学
遗传学
染色体复制控制
细胞生物学
作者
Maximilian Ehrenfeld,Felicia Segeth,Klaus Mantwill,Corinna Brockhaus,Yuling Zhao,Christian Ploner,Andreas Kolk,Jürgen E. Gschwend,Roman Nawroth,Per Sonne Holm
摘要
E1-deleted AdV vectors are considered replication deficient and are important tools for the study of virus biology, gene therapy, and large-scale vaccine development. However, deletion of the E1 genes does not completely abolish viral DNA replication in cancer cells.
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