作者
Caitlin A. McIntyre,Adrien Grimont,Jiwoon Park,Yinuo Meng,Whitney J. Sisso,Kenneth Seier,Gun Ho Jang,Henry Walch,Victoria G. Aveson,David J. Falvo,William B. Fall,Christopher W Chan,Andrew Wenger,Brett L. Ecker,Alessandra Pulvirenti,Rebecca Gelfer,María Paz Zafra,Nikolaus Schultz,Wungki Park,Eileen M. O’Reilly,Shauna L Houlihan,Alicia Alonso,Erika Hissong,George M. Church,Christopher E. Mason,Despina Siolas,Faiyaz Notta,Mithat Gönen,Lukas E. Dow,William R. Jarnagin,Rohit Chandwani
摘要
KRAS mutations in pancreatic ductal adenocarcinoma (PDAC) are suggested to vary in oncogenicity but the implications for human patients have not been explored in depth. We examined 1,360 consecutive PDAC patients undergoing surgical resection and find that KRAS