An Efficient and General Synthesis of Primary Amines by Ruthenium‐Catalyzed Amination of Secondary Alcohols with Ammonia

Angewandte Chemie International EditionVolume 49, Issue 44 p. 8126-8129 Communication An Efficient and General Synthesis of Primary Amines by Ruthenium-Catalyzed Amination of Secondary Alcohols with Ammonia† Sebastian Imm, Sebastian Imm Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this authorSebastian Bähn, Sebastian Bähn Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this authorLorenz Neubert, Lorenz Neubert Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this authorDr. Helfried Neumann, Dr. Helfried Neumann Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this authorProf. Dr. Matthias Beller, Prof. Dr. Matthias Beller matthias.beller@catalysis.de Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this author Sebastian Imm, Sebastian Imm Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this authorSebastian Bähn, Sebastian Bähn Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this authorLorenz Neubert, Lorenz Neubert Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this authorDr. Helfried Neumann, Dr. Helfried Neumann Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this authorProf. Dr. Matthias Beller, Prof. Dr. Matthias Beller matthias.beller@catalysis.de Leibniz-Institut für Katalyse an der Universität Rostock e.V. Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-51113 http://www.catalysis.deSearch for more papers by this author First published: 02 August 2010 https://doi.org/10.1002/anie.201002576Citations: 243 † This work was supported by the BMBF (Bundesministerium für Bildung und Forschung) and the Deutsche Forschungsgemeinschaft (Leibniz prize to M.B.). Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Atom efficiency and selectivity are the key features of the first homogeneously catalyzed amination of secondary alcohols with ammonia to give the corresponding primary amines (see scheme). This novel amination method relies on the commercially available catalyst [Ru3(CO)12]/cataCXium PCy and does not require any additional source of hydrogen. Citing Literature Supporting Information Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description anie_201002576_sm_miscellaneous_information.pdf138.9 KB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume49, Issue44October 25, 2010Pages 8126-8129 RelatedInformation