医学
肾炎
病理
肾活检
间质性肾炎
肾小球肾炎
肾脏疾病
蛋白尿
贫血
活检
肾脏病理学
肾
内科学
作者
Ulf Schönermarck,C Schirren,Nouhad Mistry‐Burchardi,Mark A. Weiss,Peter Eichhorn,W. Samtleben
出处
期刊:Clinical Nephrology
[Dustri-Verlag Dr. Karl Feistle]
日期:2005-11-01
卷期号:64 (11): 383-386
被引量:7
摘要
We present the case of a 75-year-old female with weight loss, anemia, systemic signs of inflammation, mild renal insufficiency, microscopic hematuria, mixed glomerular and tubular proteinuria, and high titers of PR3-ANCA. Renal biopsy demonstrated interstitial nephritis with some sclerosed but otherwise normal glomeruli. Extensive work-up showed no signs of granulomatous inflammation or other vasculitic organ involvement. We presumed this to be a rare renal manifestation of ANCA-associated disease with the presence of sclerosed glomeruli suggesting a previous history of glomerular involvement. In view of the absence of active vasculitic or granulomatous disease, treatment was limited to low-dose corticosteroids with good response.
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