医学
大流行
疾病
年轻人
青少年皮肌炎
少年
心理弹性
2019年冠状病毒病(COVID-19)
老年学
人口学
传染病(医学专业)
内科学
心理学
社会学
生物
心理治疗师
遗传学
作者
Ayesha Khatun,Wing Han Wu,Junjie Peng,Laura Hennelly,Melanie Sloan,Michael Bosley,Paul Howard,Liz Jury,Coziana Ciurtin
出处
期刊:Rheumatology
[Oxford University Press]
日期:2021-04-01
卷期号:60 (Supplement_1)
标识
DOI:10.1093/rheumatology/keab247.116
摘要
Abstract Background/Aims The impact of the COVID-19 pandemic on adolescent and young patients with chronic diseases is likely to be multi-factorial, and influenced by various aspects, such as age, sex, education, ethnicity, as well as disease control or personal coping strategies. Adolescents and young adults are at a time in their live when disruption in their education and social life, as well as uncertainty related to professional prospects and long-term disease outcomes are all associated with significant personal concerns. The aim of this survey was to assess the main determinants of COVID-19 associated concern in adolescent and young adults with JSLE and JDM as well as their well-being and resilience. Methods Questionnaires comprising of questions related to patient and disease characteristics, wellbeing, resilience and concern about the COVID-19 pandemic were disseminated through hospital contacts and patient charities social media platforms. Participation was voluntary and implied consent. The preliminary results of this ongoing survey have been analysed using descriptive statistics and linear regression (R). Results The main patient and disease characteristics, self-reported well-being, resilience and perceived concern about the COVID-19 pandemic are presented in comparison in male vs. female patients. Linear regression showed that the strongest determinant of COVID-19 concern was self-reported disease activity (p < 0.0003). The self-reported disease activity was associated with the COVID-19 concern level in both female (P = 0.003) and male patients (p = 0.004) and also with disease duration in males (P = 0.018). The COVID concern was not affected by any other factors such as, employment, education, well-being or resilience. Conclusion The preliminary analysis of our survey showed that patient-reported COVID-19 concern during the pandemic was strongly determined by the self-reported disease activity irrespective of patients’ sex, despite significantly increased concern in the female compared to male patients, and association with disease duration in male patients only. We propose that further strategies for better patient support during the pandemic should focus on their optimal disease control as well as take into consideration the sex-biased patient concerns. P120 Table 1:FemaleMalep-valueNumber389Current age mean (IQR)22.21 (18.25- 25.75)18.89 (14.00-26.00)Age at diagnosis years mean (IQR)13.01 (9.00-15.00)9.333 (7.00-11.00)Disease durationMean (IQR)9.197 (4.000-13.000)9.556 (2.000-13.000)0.4841Ethnicity;WhiteNon-white25 (65.8%)13 (34.2%)7 (77.8%)2 (22.2%)0.4841Location;England (%)Other (%)35 (92.1%)3 (7.9%)9 (100%)0 (0%)0.2578091Well-being(VAS -2 to + 2)mean (IQR)-0.6765 (-2.0000 – 0.0000)-0.4286 (-1.0000 – 0.0000)0.5667Resilience (VAS 1-7)mean (IQR)4.906 (4.000 - 6.000)5.0 (4.5 - 5.5)0.8718Self-reported disease activity (VAS 1-100)mean (IQR)35.32 (15.00- 53.00)18.67 (3.00-25.00)0.06429Self-reported COVID concern (VAS 1-100)mean (IQR)62.92 (50.00-80.00)32.33 (15.00- 40.00)0.01052Still in educationNoYesNot recorded16 (42.1%)18 (47.4%)4 (10.5%)3 (33.3%)4 (44.4%)2 (22.2%)Currently workingNoYesNot recorded24 (63.2%)10 (26.3%)4 (10.5%)5 (55.6%)2 (22.2%)2 (22.2%) Funding statement: This work was supported by Versus Arthritis (21593) Disclosure A. Khatun: None. W. Wu: None. J. Peng: None. L. Hennelly: None. M. Sloan: None. M. Bosley: None. P. Howard: None. L. Jury: None. C. Ciurtin: None.
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