Evidence for the Formation and Structure of Palladacycles during Pd‐Catalyzed CN Bond Formation with Catalysts Derived from Bulky Monophosphinobiaryl Ligands

The structural origins of the differences in catalytic activity observed between catalysts containing 2′-substituted and 2′,6′-disubstituted biaryl monophosphane ligands for a Pd-catalyzed CN bond-forming reaction are discussed. It is shown that palladacycle formation is avoided and optimal catalyst activity is achieved through the use of the 2′,6′-disubstituted ligands. (tAm=tert-amyl, dppe=1,2-bis(diphenylphosphanyl)ethane). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z502927_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.