微泡
药物输送
脂质体
体内分布
化学
纳米技术
纳米颗粒
小泡
外体
生物利用度
细胞凋亡
癌症研究
药品
细胞生物学
毒品携带者
药理学
材料科学
生物
生物化学
体外
小RNA
基因
膜
作者
Parisa Sarvarian,Parisa Samadi,Elham Gholipour,Karim Shams Asenjan,Mohammad Hojjat‐Farsangi,Roza Motavalli,Farhad Motavalli Khiavi,Mehdi Yousefi
标识
DOI:10.1080/08820139.2021.1891094
摘要
Nanotechnology has enabled the delivery of small molecular drugs packaged in nanosized vesicles to the target tissues. Plant-Derived Nanoparticles (PDNPs) are vesicles with natural origin and unique properties. These nanoparticles have several advantages over synthetic exosomes and liposomes. They provide bioavailability and biodistribution of therapeutic agents when delivered into different tissues. These nanoparticles can be modified according to the specificity of their functions in target tissues. When PDNPs are internalized, they can induce stem cells proliferation, reduce colitis injury, activate intrinsic and extrinsic apoptosis pathways, and inhibit tumor growth and progression. These properties make them potential drug delivery systems in targeting diseased tissues, such as inflammatory regions and different cancers.
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