抛光
支架
微观结构
材料科学
表面光洁度
表面粗糙度
制作
等轴晶
生物医学工程
复合材料
医学
外科
替代医学
病理
作者
Ran He,Xueqian Cao,Enzoh Langi,Lukas Masseling,Felix Vogt,Liguo Zhao
出处
期刊:Biomaterials advances
日期:2024-05-01
卷期号:159: 213835-213835
标识
DOI:10.1016/j.bioadv.2024.213835
摘要
Additive manufacturing (AM) technology has paved the way for manufacturing personalised stents. However, there is a notable gap in comprehensive microstructure analyses and in vitro evaluations of the AM CoCr stents using advanced methodologies. To address this gap, this study focuses on investigating the microstructure and in vitro performance of personalised CoCr stents manufactured through micro-laser powder bed fusion (μ-LPBF). The evaluation process begins with the measurements of dimensions and surface roughness, followed by in-depth microstructural analyses. To improve surface roughness and reduce excessive strut size, the μ-LPBF stents undergo electrochemical polishing. Importantly, in vitro stent deployments are carried out in artificial arteries manufactured based on actual patients' data. Compared to the commercial MULTI-LINK VISION CoCr stent, the μ-LPBF personalised stents have rough surface finish (average roughness: 1.55 μm for μ-LPBF vs. 1.09 μm for commercial) and compromised grain microstructures (elongated for μ-LPBF vs. equiaxed for commercial). However, the personalised stents demonstrate better performances in in vitro tests. Notably, compared to the commercial stent in the two studied cases, they deliver larger lumen gains (up to 11.24 %) and reduced recoils (up to 4 times). This study validates the merit of the lesion-specific designs and the feasibility of using AM technology for stent fabrication.
科研通智能强力驱动
Strongly Powered by AbleSci AI