溶解
剂型
生化工程
计算机科学
溶解试验
纳米技术
工艺工程
化学
材料科学
工程类
色谱法
物理化学
生物制药分类系统
作者
Jiajia Gengji,Tao Gong,Zhirong Zhang,Li Deng,Yao Fu
标识
DOI:10.1016/j.jconrel.2023.08.013
摘要
Classic methods for evaluating the disintegration and dissolution kinetics of solid dosage forms are no longer sufficient to meet the growing demands in the pharmaceutical field. Hence, scientists have turned to imaging techniques and computer technology to develop innovative visualization methods. These methods allow for a visual understanding of the disintegration or dissolution process and offer valuable insights into the drug release kinetics. This article aims to provide an overview of the commonly used imaging techniques and their applications in studying the disintegration or dissolution of solid dosage forms. Therefore, imaging presents a novel and alternative approach to understanding the mechanisms of disintegration and dissolution in the formulation study of solid dosages.
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