鲍曼不动杆菌
质粒
生物
抗生素耐药性
多重耐药
抗生素
基因
不动杆菌
微生物学
计算生物学
遗传学
细菌
铜绿假单胞菌
作者
Valerie Intorcia,Rosa L. Sava,Grace P. Schroeder,Michael J. Gebhardt
摘要
The continued emergence of antibiotic resistance among bacterial pathogens remains a significant challenge. Indeed, the enhanced antibiotic resistance profiles of contemporary pathogens often restrict the number of suitable molecular tools that are available. We have constructed a series of plasmids that confer resistance to two infrequently used antibiotics with variants of each plasmid backbone incorporating several regulatory control systems. The regulatory systems include both commonly used systems based on the
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