医学
痴呆
疾病
肌萎缩侧索硬化
失智症
全基因组关联研究
路易体
孟德尔随机化
生物信息学
生物
内科学
单核苷酸多态性
遗传学
基因
基因型
遗传变异
作者
Yi‐Jun Ge,Ya‐Nan Ou,Yue‐Ting Deng,Bang‐Sheng Wu,Yang Liu,Ya-Ru Zhang,Shi-Dong Chen,Yu‐Yuan Huang,Qiang Dong,Lan Tan,Jin‐Tai Yu,Raffaele Ferrari,Dena Hernandez,Michael A. Nalls,Jonathan D. Rohrer,Adaikalavan Ramasamy,John B. Kwok,Carol Dobson‐Stone,William S. Brooks,Peter R. Schofield
标识
DOI:10.1016/j.biopsych.2022.11.002
摘要
Neurodegenerative diseases are among the most prevalent and devastating neurological disorders, with few effective prevention and treatment strategies. We aimed to integrate genetic and proteomic data to prioritize drug targets for neurodegenerative diseases.
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