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PI3K/AKT/mTOR通路
mTORC2型
图像(数学)
人工智能
生物
细胞生物学
计算机科学
信号转导
mTORC1型
操作系统
作者
Robert A. Saxton,David M. Sabatini
出处
期刊:Cell
[Elsevier]
日期:2017-04-01
卷期号:169 (2): 361-371
被引量:1652
标识
DOI:10.1016/j.cell.2017.03.035
摘要
(Cell 168, 960–976; March 9, 2017) Due to a production error, earlier drafts of the figures in this Review were originally published in print and online. Though these were not the final versions of the figures, the information that they contained was accurate and complete. The figures have now been updated online. We apologize for any confusion caused by this error.Figure 1mTORC1 and mTORC2 (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 2The mTOR Signaling Network (corrected)View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 2The mTOR Signaling Network (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 3Evolutionary Conservation of the TOR Pathway (corrected)View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 3Evolutionary Conservation of the TOR Pathway (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 4Physiological Roles of mTOR (corrected)View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 4Physiological Roles of mTOR (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 5mTOR in Cancer and Aging (corrected)View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 5mTOR in Cancer and Aging (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT) mTOR Signaling in Growth, Metabolism, and DiseaseSaxton et al.CellMarch 09, 2017In BriefRecent advances in our understanding of mTOR regulation and functional importance highlight the contribution of mTOR-signaling network to pathogenesis in humans, raising the prospect for targeting mTOR for therapeutic development. Full-Text PDF Open Archive
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