病理
软骨
医学
透明软骨
关节病
发病机制
透明质
滑膜关节
关节炎
关节软骨
基质(化学分析)
弯月面
解剖
骨关节炎
外科
化学
替代医学
色谱法
物理
光学
入射(几何)
出处
期刊:The journal of bone and joint surgery
[British Editorial Society of Bone and Joint Surgery]
日期:1981-11-01
卷期号:63-B (4): 601-609
被引量:164
标识
DOI:10.1302/0301-620x.63b4.7298694
摘要
Specimens of tissue from haemophilic synovium and articular cartilage were collected from 39 patients during reconstructive surgery. They were studied by histochemistry, electron microscopy and microprobe analysis. The detailed findings are presented and discussed. It is suggested that haemophilic arthropathy is the result of a number of mechanisms affecting the synovial lining which becomes progressively fibrotic and the hyaline cartilage which disintegrates and is eventually lost. Mechanical and chemical processes cause degeneration of cells but enzymatic processes appear to be primarily responsible for the degradation of the matrix of the articular cartilage.
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