Prognosis of Postviral Olfactory Loss: Follow-up Study for Longer than One Year

医学 嗅觉减退 嗅觉系统 嗅觉缺失 电话采访 病历 鼻子 外科 内科学 疾病 2019年冠状病毒病(COVID-19) 精神科 社会科学 社会学 传染病(医学专业)
作者
Doh Young Lee,Woo Hyun Lee,Jee Hye Wee,Jeong‐Whun Kim
出处
期刊:American Journal of Rhinology & Allergy [SAGE]
卷期号:28 (5): 419-422 被引量:80
标识
DOI:10.2500/ajra.2014.28.4102
摘要

Background There have been very few studies on the prognosis of postviral olfactory dysfunction. The aim of the study was to evaluate its long-term prognosis and factors influencing the prognosis. Methods This study included patients who were diagnosed with postviral olfactory dysfunction at least one year ago in a Smell and Taste Clinic and whose telephone interviews were available. Their medical records were reviewed, and they were asked to score their subjective olfactory function on a 100-point scale by telephone interview. Results A total of 63 patients and 20 normal controls without nasal pathology were included. The mean of the patients was 49.5 years, and 19 males and 44 females were included. The mean length of follow-up was 33.4 months. Olfactory dysfunction was subjectively improved in 85.7% of the patients. The recovery rate to subjective normosmia was 31.7%. The mean symptom scores for smell significantly increased in comparison with baseline from 25.6 to 69.0. Among the 25 patients (37.7%) who underwent follow-up butanol threshold test (BTT), the score improved from 4.6 to 7.3. Olfactory improvement was more frequently reported by females (p = .003) and in patients with follow-up duration for longer than 2 years (p = .043). Conclusions Follow-up of postviral olfactory loss revealed that over 80% of the patients reported subjective recovery after one year. The more favorable prognosis was associated with longer follow-up duration and female gender.
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