Development and Microbiological Evaluation of Natural Diaper Rash (Diaper Dermatitis) Cream Formulations

尿布皮炎 皮肤病科 医学 皮疹
作者
Ahmet Arif Kurt,Bashar Ibrahım
出处
期刊:Journal of immunology and clinical microbiology [ScopeMed]
卷期号:9 (1): 1-11
标识
DOI:10.58854/jicm.1402773
摘要

Backround: Rosa damascena Mill, released into the environment as waste in rose products production facilities, contains antioxidant, antimicrobial, and antiseptic phenolic components. It is the development of an effective natural cream formulation for baby diaper rash by taking advantage of the antimicrobial properties of rose pulp and adding natural ingredients (zinc oxide ZnO, natural oils, and beeswax). Material and Methods: The emulsification method was used to prepare diaper rash cream formulations. Rotational type viscosity determination was performed to examine the rheological behavior of the formulations. In selecting the optimum formulation, pH, viscosity, hydrophilic-lipophilic balance, and physical appearance of the product were considered. To examine its stability properties, its stability was examined in three different environments in line with ICH directives for 6months. The optimum DR-C-7 formulation was subjected to physicochemical and stability tests. Results: It was observed that the DR-C-7 formulation had a viscosity between 9,820 and 26,130 (Pa.s) in terms of rheological properties. As a result of the challenge test, no microbiological units were found. At the end of a 6-month stability study under different conditions, it was observed that it retained all its features. Conclusion: It was concluded that R. damascena pulp, which has important phenolic contents such as phenylethyl alcohol, flavonoids, and terpenoids, can be used for thick products such as diaper rash cream with its antioxidant antimicrobial properties.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
1秒前
香菜完成签到,获得积分10
2秒前
2秒前
3秒前
领导范儿应助氨甲酰磷酸采纳,获得10
4秒前
fqh发布了新的文献求助10
5秒前
skippy完成签到 ,获得积分10
6秒前
斯文败类应助科研小白采纳,获得10
6秒前
8秒前
12秒前
12秒前
所所应助嗝额额呃呃呃采纳,获得10
12秒前
爆米花应助lucky采纳,获得10
14秒前
zeyin发布了新的文献求助10
14秒前
Orange应助可爱的王女士采纳,获得30
14秒前
英俊的铭应助科研通管家采纳,获得10
16秒前
科研通AI2S应助科研通管家采纳,获得10
16秒前
科目三应助科研通管家采纳,获得10
16秒前
思源应助科研通管家采纳,获得10
16秒前
泥泥应助斯文的碧采纳,获得10
16秒前
天天快乐应助科研通管家采纳,获得10
16秒前
陈陈完成签到 ,获得积分10
16秒前
16秒前
16秒前
Lucas应助科研通管家采纳,获得10
16秒前
17秒前
泥泥应助阿白采纳,获得10
17秒前
18秒前
小蜗发布了新的文献求助10
19秒前
星辰大海应助啥也不会采纳,获得30
21秒前
22秒前
rr完成签到,获得积分10
23秒前
SUE发布了新的文献求助10
24秒前
好运藏在善良里应助躺赢采纳,获得10
27秒前
29秒前
31秒前
33秒前
34秒前
GATT发布了新的文献求助10
35秒前
高分求助中
Spray / Wall-interaction Modelling by Dimensionless Data Analysis 2000
ALA生合成不全マウスでの糖代謝異常の分子機構解析 520
安全防范技术与工程 500
Mathematics and Finite Element Discretizations of Incompressible Navier—Stokes Flows 500
A real-time energy management strategy based on fuzzy control and ECMS for PHEVs 400
2024 Medicinal Chemistry Reviews 400
Актуализированная стратиграфическая схема триасовых отложений Прикаспийского региона. Объяснительная записка 360
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3191505
求助须知:如何正确求助?哪些是违规求助? 2840825
关于积分的说明 8030408
捐赠科研通 2504207
什么是DOI,文献DOI怎么找? 1337556
科研通“疑难数据库(出版商)”最低求助积分说明 638102
邀请新用户注册赠送积分活动 606622