Use of Antimicrobial-Coated Catheters in Preventing Catheter-Associated Urinary Tract Infections and Bacteriuria: A Meta-Analysis for Clinicians

No AccessUrology PracticePatient Care1 Nov 2021Use of Antimicrobial-Coated Catheters in Preventing Catheter-Associated Urinary Tract Infections and Bacteriuria: A Meta-Analysis for CliniciansThis article is commented on by the following:Editorial CommentaryEditorial Commentary Rachel Vopni, Alesia Voice, Cornelia S. de Riese, John Garza, and Werner T. de Riese Rachel VopniRachel Vopni Texas Tech University Health Sciences Center, Department of Urology, Lubbock, Texas More articles by this author , Alesia VoiceAlesia Voice Texas Tech University Health Sciences Center, Department of Urology, Lubbock, Texas More articles by this author , Cornelia S. de RieseCornelia S. de Riese Texas Tech University Health Sciences Center, Department of Obstetrics and Gynecology, Odessa, Texas More articles by this author , John GarzaJohn Garza Department of Mathematics, University of Texas, Permian Basin, Odessa, Texas More articles by this author , and Werner T. de RieseWerner T. de Riese *Correspondence: Department of Urology, Texas Tech University Health Sciences Center, 3601—4th Street STOP 7260, Lubbock, Texas 79430 telephone: 806-743-3862; E-mail Address: [email protected] http://orcid.org/0000-0003-1963-2334 Texas Tech University Health Sciences Center, Department of Urology, Lubbock, Texas More articles by this author View All Author Informationhttps://doi.org/10.1097/UPJ.0000000000000254AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Introduction: Catheter-associated urinary tract infections comprise a significant burden to the health care system and are of major concern for indwelling catheter use. Catheter coatings have been studied for their potential to reduce risk of infection. The purpose of this meta-analysis is to determine the efficacy of coated catheters across clinical studies in preventing these common nosocomial infections. Methods: Searches were conducted on PubMed Central® and ScienceDirect using the terms “catheter,” “urinary tract infection” and “coated” or “antimicrobial.” Articles included were prospective randomized clinical studies of coated (experimental) vs uncoated (control) catheters published in English between the years 2000 and 2020. Results from included studies were analyzed using Fisher’s exact test and conditional logistic regression. Results: Fifteen studies met the inclusion criteria. Tested urinary catheter coatings include silver, silver salt, nitrofurazone and metal-alloy. Conditional logistic regression (p <0.001) shows statistically significant negative association between coated catheter use and the incidence of catheter-associated urinary tract infections. The odds ratio of 0.80 and 95% confidence interval (0.74, 0.88) support protective effect of catheter coatings. Conclusions: Meta-analysis demonstrates a negative association of coated catheter and incidence of catheter-associated urinary tract infections, supporting that antimicrobial catheter coatings decreases incidence of infection across studies. Further clinical research is recommended to determine the potential for catheter coating adoption in clinical practice to reduce catheter-associated urinary tract infection risk and incidence. References 1. : A review of the recent advances in antimicrobial coatings for urinary catheters. Acta Biomater 2017; 50: 20. Google Scholar 2. : Materials for urinary catheters: a review of their history and development in the UK. Med Eng Phys 2005; 27: 443. 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This study was deemed exempt from IRB review. © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsRelated articlesUrology Practice18 Aug 2021Editorial CommentaryUrology Practice18 Aug 2021Editorial Commentary Volume 8Issue 6November 2021Page: 705-712 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.Keywordsprimary preventionurinary cathetersanti-infective agentsurinary tract infectionsMetricsAuthor Information Rachel Vopni Texas Tech University Health Sciences Center, Department of Urology, Lubbock, Texas More articles by this author Alesia Voice Texas Tech University Health Sciences Center, Department of Urology, Lubbock, Texas More articles by this author Cornelia S. de Riese Texas Tech University Health Sciences Center, Department of Obstetrics and Gynecology, Odessa, Texas More articles by this author John Garza Department of Mathematics, University of Texas, Permian Basin, Odessa, Texas More articles by this author Werner T. de Riese Texas Tech University Health Sciences Center, Department of Urology, Lubbock, Texas *Correspondence: Department of Urology, Texas Tech University Health Sciences Center, 3601—4th Street STOP 7260, Lubbock, Texas 79430 telephone: 806-743-3862; E-mail Address: [email protected] More articles by this author Expand All Submitted April 13, 2021. The Authors have no conflicts of interest to disclose. This study was deemed exempt from IRB review. Advertisement PDF downloadLoading ...