The Pathogenesis and Management of Acne-Induced Post-inflammatory Hyperpigmentation

痤疮 皮肤病科 医学 色素沉着 红斑 色素沉着障碍 黄褐斑
作者
Nada Elbuluk,Pearl E. Grimes,Anna L. Chien,Iltefat Hamzavi,Andrew Alexis,Susan C. Taylor,Noelani González,Jonathan S. Weiss,Seemal R. Desai,Sewon Kang
出处
期刊:American Journal of Clinical Dermatology [Adis, Springer Healthcare]
卷期号:22 (6): 829-836 被引量:51
标识
DOI:10.1007/s40257-021-00633-4
摘要

Acne vulgaris is a common inflammatory disease. Among patients with darker skin phototypes (Fitzpatrick III–VI), the inflammatory processes of acne stimulate excess melanogenesis and abnormal melanin deposition, leading to pigmentary sequelae known as post-inflammatory hyperpigmentation and post-inflammatory erythema in all skin tones, although post-inflammatory hyperpigmentation is more common in darker skin and post-inflammatory erythema in lighter skin. These pigmentary alterations can be long lasting and are often more distressing to patients than the active acne lesions. This article discusses what is known about acne-related pigmentation, much of which is extrapolated from general study of nonspecific pigment deposition. Because dyspigmentation poses both a significant clinical concern to patients and a therapeutic challenge to clinicians, we formed a working group consisting of pigmentary experts with the aim of increasing awareness and education of acne-related pigmentary sequelae.
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