Synthesis, Characterization And Antimicrobial Activity of Copper-Metal Organic Framework (Cu-MOF) And Its Modification By Melamine

Abstract Copper- Metal organic framework (Cu-MOF) and melamine/ Cu-MOF (MCu-MOF) samples were prepared by the hydrothermal process. The produced powder was dried and characterized by using the FTIR, X-ray techniques. The thermal gravimetry (TG) analysis was performed to detect the thermal stability of the product. On other hand, the morphology and the surface area of the powder were carried. The bioactivity of the powder was carried by measuring the inhibition zone diameter around samples in (mm). The results of characterization showed that the formation of Cu-MO and melamine/ Cu-MOF in crystalline state in both samples, the surface area of Cu-MOF is equal to 1350 m 2 g -1 while increase to 1410 m 2 g -1 by incorporate by melamine into the Cu-MOF. The thermal behavior (TG) of the Cu-MOF showed three sequence stages attributed to the moisture evaporation, degradation of the Cu-MOF and forming the Cu-O as end product respectively. For melamine incorporated to Cu-MOF (MCu-MOF), the TG profile shows that the split of the main degradation into two parts resulting from the presence of melamine. The bioactivities of the both samples were tested against microbial strains. The results showed that the Cu-MOF and MCu-MOF have insignificant antimicrobial activity against gram positive of bacteria and Fungi. While for gram negative of bacteria it is observed a considerable effect.