已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Absolute Neutrophil Count in Cases of Pancytopenia.

全血细胞减少症 医学 再生障碍性贫血 中性粒细胞绝对计数 阵发性夜间血红蛋白尿 巨幼细胞性贫血 内科学 儿科 胃肠病学 贫血 外科 骨髓 中性粒细胞减少症 化疗
作者
Mathews N Mathew,Kundan Mishra,Kanwaljeet Singh,Suman Kumar Parmanik
出处
期刊:PubMed 卷期号:70 (4): 11-12
链接
标识
摘要

Pancytopenia is a common cause of hematological consultation. Common underlying causes include vitamin deficiency (vitamin B12, folic acid), drugs (hydroxyurea, phenytoin, methotrexate), and bone marrow failure syndrome. Aplastic anemia is one of the rarest hematological diseases and presents as pancytopenia. However, it is the most sinister one and is a hematological emergency that needs urgent medical attention. Absolute neutrophil count (ANC) is a measure of disease severity and is expected to be low in patients with pancytopenia of any cause. Aim & Objective: We aimed to analyze the absolute neutrophil count (ANC) level in patients presenting with pancytopenia. Material & Method: This prospective, observational study was conducted at a tertiary care hospital in northern India. We included patients with pancytopenia diagnosed at our center or reported to our center for therapy. ANC was measured before starting therapy. Observation: One hundred twenty-seven patients were included in this study. After evaluation, megaloblastic anemia was the commonest underlying cause in 42 (33%) patients followed by myelodysplastic syndrome in 31 (24.4%) patients. Twenty-three (18.1%) patients having pancytopenia were diagnosed with aplastic anemia. Other causes included leukemia, paroxysmal nocturnal hemoglobinuria and drugs. The median age was 37 years (range 18-75 years), and 67 (52.75%) were male. The mean hemoglobin was 5.5 g/dL (95% CI ±1.9). The median WBC was 2570/cmm (300-3130) and the median platelet was 36000/cmm (2000-92000). The median ANC in patients with aplastic anemia was 594/cmm (range 25- 3850). When compared, the ANC level was significantly lower in aplastic anemia than other causes of pancytopenia (p<0.001). Conclusion: On univariate and multivariate analysis ANC was significantly lower at baseline in patients of aplastic anemia. A longer follow-up of the patients will be required to assess the value of ANC in predicting response to therapy.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
缥缈熊猫完成签到 ,获得积分10
1秒前
大妙妙完成签到 ,获得积分10
1秒前
张鱼小丸子完成签到,获得积分20
3秒前
briliian完成签到,获得积分10
4秒前
英姑应助Persist采纳,获得10
6秒前
小二郎应助Persist采纳,获得10
6秒前
Jemma完成签到 ,获得积分10
8秒前
小象完成签到,获得积分10
10秒前
谨慎颜演完成签到 ,获得积分10
10秒前
程新亮完成签到 ,获得积分10
11秒前
肖治民完成签到,获得积分10
12秒前
bioinformation完成签到,获得积分10
14秒前
HuFan1201完成签到 ,获得积分10
14秒前
大气金毛完成签到 ,获得积分10
18秒前
吃菠萝的桃子完成签到,获得积分10
18秒前
无花果应助swh采纳,获得10
20秒前
22秒前
尼美舒利完成签到 ,获得积分10
25秒前
25秒前
明亮不乐完成签到,获得积分20
26秒前
28秒前
有缘人完成签到,获得积分10
30秒前
风清扬发布了新的文献求助10
31秒前
swh发布了新的文献求助10
32秒前
不吃番茄完成签到 ,获得积分10
33秒前
婷123完成签到 ,获得积分10
34秒前
天天快乐应助平常的芝麻采纳,获得30
36秒前
指导灰完成签到 ,获得积分10
36秒前
Jes发布了新的文献求助10
36秒前
爆米花应助肖治民采纳,获得10
39秒前
李健的小迷弟应助小远采纳,获得20
39秒前
JamesPei应助风清扬采纳,获得10
42秒前
46秒前
温柔的柠檬完成签到 ,获得积分10
47秒前
blingbling完成签到,获得积分20
48秒前
思源应助科研通管家采纳,获得10
48秒前
NexusExplorer应助科研通管家采纳,获得10
48秒前
blingbling发布了新的文献求助10
52秒前
52秒前
慕青应助萤lueluelue采纳,获得10
54秒前
高分求助中
The Mother of All Tableaux Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 2400
Ophthalmic Equipment Market by Devices(surgical: vitreorentinal,IOLs,OVDs,contact lens,RGP lens,backflush,diagnostic&monitoring:OCT,actorefractor,keratometer,tonometer,ophthalmoscpe,OVD), End User,Buying Criteria-Global Forecast to2029 2000
Optimal Transport: A Comprehensive Introduction to Modeling, Analysis, Simulation, Applications 800
Official Methods of Analysis of AOAC INTERNATIONAL 600
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 588
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
T/CIET 1202-2025 可吸收再生氧化纤维素止血材料 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3956962
求助须知:如何正确求助?哪些是违规求助? 3503011
关于积分的说明 11111001
捐赠科研通 3234007
什么是DOI,文献DOI怎么找? 1787710
邀请新用户注册赠送积分活动 870713
科研通“疑难数据库(出版商)”最低求助积分说明 802234