酒精性肝病
胃肠病学
小肠细菌生长过度
内科学
医学
肝硬化
入射(几何)
氢呼气试验
酗酒
肝病
酒
慢性肝病
呼吸试验
幽门螺杆菌
生物
肠易激综合征
精神科
物理
生物化学
光学
作者
Christiane Bode,R. Kolepke,Katharina Schäfer,Bode Jc
出处
期刊:PubMed
日期:1993-01-01
卷期号:31 (1): 3-7
被引量:76
摘要
The hydrogen breath test has been used to investigate the incidence of small-bowel bacterial overgrowth in 45 chronic alcoholics and in 60 controls with no history of alcohol abuse. In the group of patients with alcoholic liver disease, the percentage of cases with bacterial overgrowth was almost three times (37.8%) that of controls not abusing alcohol (13.3%; p < 0.001). A separate evaluation of alcoholics with cirrhosis in comparison with those without cirrhosis, revealed no significant difference in the incidence of bacterial overgrowth (42.9% and 33.3%; p > 0.05). Some 16.7% of the controls and 8.9% of the patients with alcoholic liver disease were classified as "non-excreters". Among patients with alcoholic liver disease, the mouth-to-caecum transit time was prolonged by 21.5% in comparison with the controls not abusing alcohol (p < 0.025). The results suggest that bacterial overgrowth might contribute to the functional and/or morphological abnormalities of the small intestine commonly found in patients with chronic alcohol abuse.
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