Advanced research on effective monomers of ophthalmological Chinese traditional medicine

Traditional Chinese medicine is the treasure of China and the people of the world.With the standardization and internationalization of traditional Chinese medicine, the effective components or monomers of Chinese herbal medicines should be clarified and investigated.Although researches on effective components of Chinese herbal medicines have been increasing year by year, there is a lack of systematic induction.In this review, we summarized the traditional Chinese medicines which have therapeutic effects on the eye diseases recorded in Chinese Pharmacopoeia (2015 edition). According to the information from published books and literature reports, the relevant bioactive constituents of these Chinese medicines and the possible mechanisms of their pharmacological actions are summarized and categorized here in 5 aspects: antipathogenic microbial action, anti-inflammation and immunomodulation, anti-oxidation, neuroprotection, and vascular protection.We hope that this review will provide some theoretical basis and reference for the researchers who are dedicated to the treatment of ophthalmic diseases and the research and development of traditional Chinese medicines. Key words: Chinese pharmacopoeia; Traditional Chinese medicine; Bioactive component; Eye diseases; Pharmacological effects