Ideal physical activity in association with incident ankylosing spondylitis: a community-based, prospective cohort study

医学 强直性脊柱炎 体质指数 前瞻性队列研究 混淆 血压 危险系数 队列研究 比例危险模型 心血管健康 队列 内科学 物理疗法 置信区间 疾病
作者
Jinmei Su,Liufu Cui,Wenhao Yang,Huijing Shi,Cheng Jin,Rong Shu,Hongfen Li,Xiaofeng Zeng,Shouling Wu,Xiang Gao
出处
期刊:Clinical and Experimental Rheumatology [Springer Vienna]
卷期号:39 (1): 73-78 被引量:3
标识
DOI:10.55563/clinexprheumatol/a6bvty
摘要

Only limited risk factors for ankylosing spondylitis (AS) have been identified to date. Therefore, we aimed to explore whether cardiovascular health (CVH) behaviours and factors are associated with the risk of developing AS.Patients with incident AS were identified in cohorts from two ongoing prospective studies. Assessments were made of the association of AS with individual baseline cardiovascular health lifestyle behaviours (including smoking status, body mass index, physical activity and diet) and cardiovascular health factors (including total cholesterol levels, blood pressure levels and fasting plasma glucose levels), and with a cardiovascular health metric determined by the number of ideal behaviours and factors. Cox regression analysis was used for the estimation of hazard ratios (HRs) for AS.Among 124,303 participants, incident AS was identified in 53 individuals within the 8 years of follow-up. For participants with ideal physical activity (>80 min/week) the HR was 0.21 (95% CI 0.05-0.89) compared with participants without ideal physical activity after adjusting for potential confounders. No signi cant risk of developing AS was associated with baseline smoking, diet, body mass index, blood pressure, fasting blood glucose or total cholesterol status, nor did cardiovascular health metrics.Adherence to ideal physical activity may reduce the risk of developing AS.
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