Sarcoidosis and Lymphoma

Letters and Corrections1 March 1984Sarcoidosis and LymphomaS. MARSH WILLIS, M.D.S. MARSH WILLIS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-3-464_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The case reported by Rosenfelt and colleagues (1) is interesting, but whether this case represents progression of sarcoidosis to malignant lymphoma is debatable. The coexistence of sarcoidosis and malignant lymphoma cannot be excluded, but another, more likely possibility is that the patient had a steroid-responsive lymphoma, even from the onset of his disease.The nonnecrotizing granuloma of sarcoidosis has been studied extensively (2). This pathologic finding is distinctive but highly nonspecific. It can be seen in various clinical situations, including infectious and inflammatory conditions; drug and chemical-induced states; other granulomatoses; and in association with malignancy. Many cases...References1. ROSENFELT F, YOUNG W, LONKEY S, and ROSENBLOOM B. Sarcoidosis progressing to lymphoma [Letter]. Ann Intern Med. 1983;99:878. LinkGoogle Scholar2. MITCHELL D, SCADDING J, and HEARD B. Sarcoidosis: histopathologic definition and clinical diagnosis. J Clin Pathol. 1977;30:395-400. CrossrefMedlineGoogle Scholar3. ROMER F. Sarcoidosis in cancer—a critical view. In: WILLIAMS WJ, DAVIES, BH, eds. Eighth International Conference on Sarcoidosis and Other Granulomatous Diseases. London: Alpha Omega Publishing, Limited; 1980:567-71. Google Scholar4. BRINCKER H. Sarcoid reactions and sarcoidosis in Hodgkin's disease and other malignant lymphomata. Br J Cancer. 1972;26:120-8. CrossrefMedlineGoogle Scholar5. PICK A, DUER D, and KESSLER H. Delayed hypersensitivity and lymphocytic transformation in patients with Hodgkin's disease and granulomas. Cancer. 1978;41:2192-6. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: S. MARSH WILLIS, M.D.Affiliations: Fitzsimons Army Medical Center Aurora, CO, 80045 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 March 1984Volume 100, Issue 3Page: 464-464KeywordsDrugsGranulomasLymphomaSarcoidosis ePublished: 1 December 2008 Issue Published: 1 March 1984 PDF downloadLoading ...