Temporal Control of Urate Oxidase Activity in Drosophila : Evidence of an Autonomous Timer in Malpighian Tubules

The appearance of urate oxidase activity in the Malpighian tubules of Drosophila melanogaster is synchronized with the time of emergence of the imago from the puparium. A developmental clock within the Malpighian tubules specifies the time of appearance of urate oxidase activity.