亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

A high visceral adipose tissue-to-skeletal muscle ratio as a determinant of major complications after pancreatoduodenectomy for cancer

医学 脂肪组织 优势比 围手术期 肌萎缩 置信区间 逻辑回归 单变量分析 腹内脂肪 曲线下面积 接收机工作特性 癌症 多元分析 内科学 放射科 肥胖 内脏脂肪 胰岛素抵抗
作者
Marta Sandini,Davide Paolo Bernasconi,Davide Fior,Matilde Molinelli,Davide Ippolito,Luca Nespoli,Riccardo Caccialanza,Luca Gianotti
出处
期刊:Nutrition [Elsevier BV]
卷期号:32 (11-12): 1231-1237 被引量:116
标识
DOI:10.1016/j.nut.2016.04.002
摘要

Complication rates after pancreatic resections remain high despite improvement in perioperative management. The effects of body composition and the relationship among different body compartments on surgical morbidity are not comprehensively investigated. The aim of this study was to assess whether the evaluation of different body compartments and their relationship was associated with the development of major postoperative complications after pancreatoduodenectomy (PD) for cancer.We retrospectively analyzed 124 patients who underwent PD and had a staging computed tomography (CT) scan at our center. CT scan was used to measure abdominal skeletal muscle area and volume, as well as visceral fat area (VFA) and volume. The total abdominal muscle area (TAMA) was then normalized for height. The severity of complications was assessed. Univariate and multivariate analyses were performed to investigate correlations between the above variables and postoperative complications. The receiver operating characteristic curve methodology was used to investigate the predictive ability of each parameter.Major complications occurred in 42 patients (33.9%). The prevalence of sarcopenia was 24.2%. Regression analyses revealed no correlation between abdominal muscular and adipose tissue areas. Univariate analysis showed that the depletion of muscle area normalized for height was not per se predictive of complications (P = 0.318). Multivariate logistic regression showed that the VFA/TAMA was the only determinant of major complications (odds ratio, 3.20; 95% confidence interval, 1.35-7.60; P = 0.008). The model predictive performance was 0.735 (area under the curve) with a sensitivity of 64.3% and a specificity of 74.4%.Sarcopenic obesity is a strong predictor of major complications after PD for cancer.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
LONG完成签到 ,获得积分10
刚刚
秋风今是完成签到 ,获得积分10
6秒前
18秒前
核桃发布了新的文献求助10
22秒前
biubiubiu驳回了852应助
51秒前
AUGKING27完成签到 ,获得积分10
1分钟前
1分钟前
1分钟前
1分钟前
无语的诗柳完成签到 ,获得积分10
1分钟前
nina完成签到 ,获得积分10
1分钟前
远山淡影_cy完成签到,获得积分20
1分钟前
康谨完成签到 ,获得积分10
1分钟前
blenx完成签到,获得积分10
1分钟前
1分钟前
小叶子完成签到 ,获得积分10
1分钟前
Liufgui应助徐悦月采纳,获得10
1分钟前
1分钟前
Dave完成签到,获得积分10
2分钟前
FashionBoy应助Dave采纳,获得10
2分钟前
2分钟前
2分钟前
2分钟前
顾矜应助Emon采纳,获得10
2分钟前
2分钟前
3分钟前
芝麻完成签到,获得积分10
3分钟前
3分钟前
Dave发布了新的文献求助10
3分钟前
大模型应助芝麻采纳,获得10
3分钟前
3分钟前
jjjjj发布了新的文献求助10
3分钟前
Liufgui应助花凉采纳,获得20
3分钟前
biubiubiu发布了新的文献求助10
3分钟前
万能图书馆应助章鱼采纳,获得10
3分钟前
jjjjj完成签到,获得积分20
3分钟前
3分钟前
章鱼发布了新的文献求助10
3分钟前
牛八先生完成签到,获得积分10
3分钟前
3分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990045
求助须知:如何正确求助?哪些是违规求助? 3532108
关于积分的说明 11256334
捐赠科研通 3270943
什么是DOI,文献DOI怎么找? 1805146
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228