化学
立体专一性
内酰胺
β-内酰胺
立体化学
口服活性
弹性蛋白酶
结构-活动关系
活动站点
生物活性
化学合成
生物化学
酶
体外
抗生素
催化作用
作者
P E Finke,Sanjiv Shah,Daniel S. Fletcher,Bonnie M. Ashe,K A Brause,G O Chandler,Pam S. Dellea,Karen M. Hand,Alan L. Maycock,D G Osinga
摘要
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrally Active .beta.-Lactam Inhibitors of Human Leukocyte Elastase. 3. Stereospecific Synthesis and Structure-Activity Relationships for 3,3-Dialkylazetidin-2-onesPaul E. Finke, Shrenik K. Shah, Daniel S. Fletcher, Bonnie M. Ashe, Karen A. Brause, Gilbert O. Chandler, Pam S. Dellea, Karen M. Hand, Alan L. Maycock, and Cite this: J. Med. Chem. 1995, 38, 13, 2449–2462Publication Date (Print):June 1, 1995Publication History Published online1 May 2002Published inissue 1 June 1995https://pubs.acs.org/doi/10.1021/jm00013a021https://doi.org/10.1021/jm00013a021research-articleACS PublicationsRequest reuse permissionsArticle Views491Altmetric-Citations78LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information Get e-Alerts
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